Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes

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Clostridium difficile 027 infection in Central Italy

BACKGROUND Clostridium difficile (CD) has increasingly become recognised as a significant international health burden, often associated with the healthcare environment. The upsurge in incidence of CD coincided with the emergence of a hypervirulent strain of CD characterized as 027. In 2010, 8 cases of CD 027 infections were identified in Italy. Since then, no further reports have been published...

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Epidemic Clostridium difficile Ribotype 027 in Chile

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Outbreaks of Clostridium difficile infections (CDI) with increased severity, high relapse rate and significant mortality have been related to the emergence of a new, hypervirulent C. difficile strain in North America and Europe. This emerging strain is referred to as PCR ribotype 027 (Type 027). Since 2005, individual countries have developed surveillance studies about the spread of type 027.C....

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Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage.

Clostridium difficile is the most common cause of antibiotic-associated diarrhoea worldwide. Over the past 10 years, the incidence and severity of disease have increased in North America and Europe due to the emergence of a hypervirulent clone designated PCR ribotype 027. In this study, we sought to identify phenotypic differences among a collection of 26 presumed PCR ribotype 027 strains from ...

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ژورنال

عنوان ژورنال: Clinical Microbiology and Infection

سال: 2019

ISSN: 1198-743X

DOI: 10.1016/j.cmi.2018.06.020